20 March 2002

Safe decay detector developed by dentists and textile experts

The University of Dundee today welcomed a boost of well over £300,000 to back radical projects with implications for beating tooth decay and disease, in the latest Proof of Concept awards announced by Minister for Enterprise, Transport and Lifelong Learning Wendy Alexander yesterday.

Tooth decay could soon be detected without resorting to potentially harmful X-rays - by using a novel electrical technique developed by dental researchers at the University of Dundee in an unusual partnership with textile experts at Heriot Watt University.

Laboratory tests show the device, which measures the electrical resistance of teeth, is twice as accurate as current examination techniques and detects decay in its earliest stages when preventive treatment is still possible.

Known as ACIST - which stands for AC impedance spectroscopy technique - the device has been developed by the Dundee team together with colleagues in St Andrews University. The sensor, which was patented in 1996, is being developed in collaboration with textile specialists at Heriot Watt University.

The Dundee and Heriot Watt teams learned yesterday they have been awarded £139,500 funding by Scottish Enterprise through the Proof of Concept Fund, to develop a prototype probe for testing. If successful it could be in the market place in two years.

The concept exploits the change in the nature of the tooth as it decays. As caries progresses microscopic pores develop in the tooth which fill with fluid that conducts current. By applying an electrically conductive strip to the tooth and passing a small electrical current through it, dentists can use the amount of resistance to the charge as a gauge of whether there is any decay .

Principal investigator Dr Chris Longbottom: "The technique is expected to be faster, safer and more accurate than X-rays which is good news for patients, dentists and the health service where it has cost-saving implications. By picking up the disease at an early stage it will also be possible in many cases to stop or even to reverse the decay thus saving more teeth."

The plastic sensor used to measure the electrical resistance is being developed by Heriot Watt's school of textiles in Galashiels who are working on a special polymer that could be inserted between the teeth like a wider type of dental floss.

The information from the sensor is fed to the electrical device and could be used by dentists instead of a traditional X-ray.

Once complete the probe will be clinically tested and assessed by dental researchers and, if successful, it could be taken to the commercial stage.

Dr Longbottom welcomed the funding award: "This funding will allow us to take an original concept which works in the laboratory and test its true potential in prototype as a first step towards possible commercialisation.

Notes for Editors

  1. The Proof of Concept Fund supports leading-edge technologies in Scotland's academic institutions and aims to help export innovation from the lab to the global marketplace.

    It was launched in 1999 as a three-year, £11m Fund; however, on the strength of its early successes and popularity, it has been trebled to £33m over a six-year period. Today, the Fund supports 82 groundbreaking projects worth £13m and has created 207 new jobs. It concentrates on early-stage ideas, which have typically reached patent level and could lead to the creation of new businesses, or licensing of innovative technologies. Successful bidders must demonstrate that their ideas have originality and true commercial potential.

    It is recognised that the projects supported are high risk and will generally take several years to become commercially viable investments; thus the Proof of Concept Fund represents a powerful commitment to encouraging Scottish innovation and exploiting research know-how to maximum effect.

    Further details on the Proof of Concept Fund and the projects that are currently supported can be found at: http://www.scottish-enterprise.com/proofofconceptfund

  2. The University of Dundee's record of turning ideas and knowledge into products and services was recognised in the LaunchIT 2001 awards in London when the university was named the fastest developing for innovation and enterprise.Research income is £43m p.a. ranking third in Scotland and sixteenth in the UK - remarkable for a university of its size. Twenty five per cent of that research income comes from industry. A strong intellectual property portfolio contains more than 80 patents, 30 of which have been licensed. University of Dundee research has led to the formation of many high profile, high growth spin out companies serving international markets. These include Axis Shield, Cyclacel, DDS Medicines, Cypex, AMCET, Innov8ive Detection and Monitoring and CXR Biosciences Ltd.

  3. 18 million dental X-rays were made in UK general practice in 1994 (latest figures of National Radiological Protection Board). Currently used methods of detection (human-eye and x-rays) pick up only 20-50% of cases and only detect the disease in its later stages.