Time for tea

Scientists working at the University's Neurosciences Institute have identified new potentially therapeutic properties in an unexpected place: black tea.

A team led by Dr Graham Rena has found that it may have the potential to help combat type 2 diabetes. Dr Rena and his team are interested in identifying agents capable of substituting for insulin in type 2 diabetes, the form of diabetes where the body stops responding to insulin properly.

In collaboration with colleagues at the Scottish Crop Research Institute the researchers discovered that several black tea constituents, known as theaflavins and thearubigins, mimicked insulin action.

"What we have found is that these constituents can mimic insulin action on proteins known as FOXOs," said Dr Rena.

"FOXOs have previously been shown to underlie associations between diet and health in a wide variety of organisms including mice, worms and fruit flies. The task now is to see whether we can translate these findings into something useful for human health."

"Our study is just the first step. If we can identify substances that restore FOXO regulation in people with type 2 diabetes, we might be able to use these to reduce the considerable burden of serious health problems associated with this diagnosis."

"This is something that needs further research and people shouldn't be rushing to drink masses of black tea thinking it will cure them of diabetes - we are still some way from this leading to new treatments or dietary advice. Our research into tea compounds is at a preclinical, experimental stage and people with diabetes should continue to take their medicines as directed by their doctor."

"However, there is definitely something interesting in the way these naturally occurring components of black tea may have a beneficial effect, both in terms of diabetes and our wider health."