12 November 2003

Chemistry and cancer

Photo opportunity 11am, Wednesday 12 November, Carnelley lecture theatre, Carnelley Building, University of Dundee.

A visiting lecturer from the US will give an insight into the chemistry of cancer today at the University of Dundee.

Professor Craig Jordan OBE will give the Royal Society of Chemistry Sosnovsky lecture entitled "Mechanisms for Multi-functional medicines to prevent breast cancer, osteoporosis and coronary heart disease."

Professor Jordan is the Diana, Princess of Wales Professor of Cancer Research and Professor Molecular Pharmacology and Biological Chemistry at the school of Medicinein Northwestern University, Chicago.

Tamoxifen is an anti-oestrogen drug (designed to counteract the effects of the hormone oestrogen). It is widely used for the treatment of breast cancer, both after an initial operation and if the cancer returns following treatment. In his lecture, Professor Jordan will discuss how anti-oestrogens such as Tamoxifen function, and how oestrogen receptors may be targeted with drugs like Tamoxifen or its chemical cousin Raloxifene for selective cancer chemotherapy or treatment of other disorders such as osteoporosis and coronary heart disease.

The development of tamoxifen for the treatment and prevention of breast cancer are among Professor Jordan's research accomplishments. Among his research interests is the recognition of selective estrogen receptor modulation, molecular mechanisms of anti-oestrogen action. Professor Jordan has published over 500 papers and books and several international awards for breast cancer research.

The lecture will take place in the Carnelley lecture theatre at 11.15am this morning.

By Jenny Marra, Head of Press 01382 344910 j.m.marra@dundee.ac.uk